Title : Genetic screens reveal CCDC115 as a modulator of erythroid iron and heme trafficking.

Pub. Date : 2020 Sep

PMID : 32510613






2 Functional Relationships(s)
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1 We deciphered a role for the vacuolar-type H+ - ATPase (V- ATPase) assembly factor CCDC115 in TBI uptake and validated this role in CCDC115 deficient K562 cells. tbi coiled-coil domain containing 115 Homo sapiens
2 Furthermore, we provided evidence that CCDC115, which we identified as required for TBI uptake, is also involved in cellular heme distribution. tbi coiled-coil domain containing 115 Homo sapiens