Title : Sevoflurane inhibits migration and invasion of glioma cells via regulating miR-34a-5p/MMP-2 axis.

Pub. Date : 2020 Sep 1

PMID : 32502543






5 Functional Relationships(s)
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1 Sevoflurane inhibits migration and invasion of glioma cells via regulating miR-34a-5p/MMP-2 axis. Sevoflurane matrix metallopeptidase 2 Homo sapiens
2 In glioma cells, sevoflurane up-regulated miR-34a-5p abundance and down-regulated MMP-2 level. Sevoflurane matrix metallopeptidase 2 Homo sapiens
3 MMP-2 was targeted via miR-34a-5p and MMP-2 silence reversed the influence of miR-34a-5p knockdown under sevoflurane. Sevoflurane matrix metallopeptidase 2 Homo sapiens
4 MMP-2 was targeted via miR-34a-5p and MMP-2 silence reversed the influence of miR-34a-5p knockdown under sevoflurane. Sevoflurane matrix metallopeptidase 2 Homo sapiens
5 Sevoflurane exposure represses cell migration and invasion, which might be related to inhibition of MMP-2 by up-regulating miR-34a-5p. Sevoflurane matrix metallopeptidase 2 Homo sapiens