Title : Variation of PD-L1 expression in locally advanced cervical cancer following neoadjuvant chemotherapy.

Pub. Date : 2020 Jun 3

PMID : 32493336






3 Functional Relationships(s)
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1 RESULTS: The fraction of patients with high PD-L1 expression was significantly increased from 32.4 to 46.5% after NAC (chi2 = 5.897, p = 0.015), while the increase of CD3+, CD4+, CD8+ TILs was not significant. nac CD274 molecule Homo sapiens
2 High PD-L1 expression was not associated with CD3+, CD4+, CD8+ TILs before NAC, however CD8+ TILs infiltration was positively associated with high PD-L1 expression after NAC (r = 0.205, p = 0.014). nac CD274 molecule Homo sapiens
3 The decreased PD-L1 expression was more observed in patients with clinical response to NAC (chi2 = 6.890, p = 0.009). nac CD274 molecule Homo sapiens