Title : Nonclinical Characterization of the Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor Roxadustat, a Novel Treatment of Anemia of Chronic Kidney Disease.

Pub. Date : 2020 Aug

PMID : 32487538






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In the PG-PS model, roxadustat significantly decreased hepatic expression of hepcidin, a hormone responsible for iron sequestration and functional iron deficiency, and increased expression of two genes involved in duodenal iron absorption: divalent metal transporter 1 and duodenal cytochrome b. roxadustat cytochrome b reductase 1 Rattus norvegicus