Pub. Date : 2020 Sep
PMID : 32472692
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Metformin mitigates gastrointestinal radiotoxicity and radiosensitises P53 mutation colorectal tumours via optimising autophagy. | Metformin | Wistar clone pR53P1 p53 pseudogene | Rattus norvegicus |
| 2 | In addition, our data indicated that metformin increased the radiosensitivity of colorectal tumours with P53 mutation both in vitro and in vivo. | Metformin | Wistar clone pR53P1 p53 pseudogene | Rattus norvegicus |
| 3 | CONCLUSION AND IMPLICATIONS: Metformin may be a radiotherapy adjuvant agent for colorectal cancers especially those carrying P53 mutation. | Metformin | Wistar clone pR53P1 p53 pseudogene | Rattus norvegicus |