Title : Combination of a p53-activating CP-31398 and an MDM2 or a FAK inhibitor produces growth suppressive effects in mesothelioma with wild-type p53 genotype.

Pub. Date : 2020 Aug

PMID : 32468177






1 Functional Relationships(s)
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1 Combination of CP-31398 and defactinib, a FAK inhibitor, also achieved synergistic inhibitory effects and increased p53 with FAK dephosphorylation levels greater than the single treatment. defactinib tumor protein p53 Homo sapiens