Title : TFAM depletion overcomes hepatocellular carcinoma resistance to doxorubicin and sorafenib through AMPK activation and mitochondrial dysfunction.

Pub. Date : 2020 Aug 30

PMID : 32461017






1 Functional Relationships(s)
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1 TFAM depletion led to inhibition of growth and survival but not migration, and sensitization to doxorubicin and sorafenib treatment, through AMPK activation, reduction of nucleoside triphosphates and mitochondrial respiration in HCC cells. nucleoside triphosphates transcription factor A, mitochondrial Homo sapiens