Pub. Date : 2020 Jul 12
PMID : 32456796
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | CD147 promotes DNA damage response and gemcitabine resistance via targeting ATM/ATR/p53 and affects prognosis in pancreatic cancer. | gemcitabine | tumor protein p53 | Homo sapiens |
| 2 | CD147 knockdown or monoclonal antibodies improved the killing effects of gemcitabine in gemcitabine resistant cells, exhibiting reduced activation of ATM/p53. | gemcitabine | tumor protein p53 | Homo sapiens |
| 3 | CD147 knockdown or monoclonal antibodies improved the killing effects of gemcitabine in gemcitabine resistant cells, exhibiting reduced activation of ATM/p53. | gemcitabine | tumor protein p53 | Homo sapiens |
| 4 | Moreover, we found the interaction of CD147 with ATM, ATR and p53, which was augmented in gemcitabine resistant cells. | gemcitabine | tumor protein p53 | Homo sapiens |