Title : Tea polyphenols protect learning and memory in sleep-deprived mice by promoting AMPA receptor internalization.

Pub. Date : 2020 Aug 12

PMID : 32453025






5 Functional Relationships(s)
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1 Tea polyphenols protect learning and memory in sleep-deprived mice by promoting AMPA receptor internalization. Polyphenols solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 Mus musculus
2 Tea polyphenols, major active compounds in green tea, suppressed TNFalpha production through downregulating TNFalpha converting enzyme (TACE) level. Polyphenols solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 Mus musculus
3 Tea polyphenols, major active compounds in green tea, suppressed TNFalpha production through downregulating TNFalpha converting enzyme (TACE) level. Polyphenols solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 Mus musculus
4 Meanwhile, tea polyphenols treatment could ameliorate recognition impairment and anxiety-like behaviors in S-DEP mice. Polyphenols solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 Mus musculus
5 The aforementioned results demonstrate cognition protective effects of tea polyphenols in S-DEP mice model, which provide a theoretical basis for the treatments of S-DEP-induced cognition impairment by targeting the TACE/TNFalpha/AMPA pathway. Polyphenols solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 Mus musculus