Title : A Phase II, Single-Arm, Open-Label, Bayesian Adaptive Efficacy and Safety Study of PBI-05204 in Patients with Stage IV Metastatic Pancreatic Adenocarcinoma.

Pub. Date : 2020 Oct

PMID : 32452588






1 Functional Relationships(s)
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1 Oleandrin, the extract"s major cytotoxic component, is a cardiac glycoside that has demonstrated antitumor activity in various tumor cell lines with a mechanism involving inhibition of Akt phosphylation and through downregulation of mTOR. oleandrin AKT serine/threonine kinase 1 Homo sapiens