Title : Thalidomide Reduces Vascular Endothelial Growth Factor Immunostaining in Canine Splenic Hemangiosarcoma.

Pub. Date : 2020 May 20

PMID : 32443710






9 Functional Relationships(s)
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1 Thalidomide Reduces Vascular Endothelial Growth Factor Immunostaining in Canine Splenic Hemangiosarcoma. Thalidomide vascular endothelial growth factor A Canis lupus familiaris
2 Recently it was demonstrated that thalidomide extends the survival time of dogs with HSA, potentially due to thalidomide-induced inhibition of vascular endothelial growth factor (VEGF) production by the neoplastic cells. Thalidomide vascular endothelial growth factor A Canis lupus familiaris
3 Recently it was demonstrated that thalidomide extends the survival time of dogs with HSA, potentially due to thalidomide-induced inhibition of vascular endothelial growth factor (VEGF) production by the neoplastic cells. Thalidomide vascular endothelial growth factor A Canis lupus familiaris
4 Recently it was demonstrated that thalidomide extends the survival time of dogs with HSA, potentially due to thalidomide-induced inhibition of vascular endothelial growth factor (VEGF) production by the neoplastic cells. Thalidomide vascular endothelial growth factor A Canis lupus familiaris
5 Recently it was demonstrated that thalidomide extends the survival time of dogs with HSA, potentially due to thalidomide-induced inhibition of vascular endothelial growth factor (VEGF) production by the neoplastic cells. Thalidomide vascular endothelial growth factor A Canis lupus familiaris
6 To investigate this, immunostaining was used to evaluate VEGF within HSA metastases that developed after thalidomide treatment. Thalidomide vascular endothelial growth factor A Canis lupus familiaris
7 This supports the hypothesis that thalidomide prolongs survival time in dogs with HSA due to inhibition of VEGF production by the neoplastic cells. Thalidomide vascular endothelial growth factor A Canis lupus familiaris
8 As VEGF remained visible within HSAs exposed to thalidomide, additional treatments to inhibit VEGF production may further prolong survival times of dogs with these common canine neoplasms. Thalidomide vascular endothelial growth factor A Canis lupus familiaris
9 As VEGF remained visible within HSAs exposed to thalidomide, additional treatments to inhibit VEGF production may further prolong survival times of dogs with these common canine neoplasms. Thalidomide vascular endothelial growth factor A Canis lupus familiaris