Title : TraPS-VarI: Identifying genetic variants altering phosphotyrosine based signalling motifs.

Pub. Date : 2020 May 21

PMID : 32439998






2 Functional Relationships(s)
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1 As such, the signalling properties of haematological transmembrane receptors rely on the membrane-proximal phosphotyrosine based sequence motifs (TBSMs) such as ITAM (immunoreceptor tyrosine-based activation motif), ITIM (immunoreceptor tyrosine-based inhibition motif) and signal transducer and activator of transcription 3 (STAT3)-recruiting YxxQ motifs. Tyrosine signal transducer and activator of transcription 3 Homo sapiens
2 As such, the signalling properties of haematological transmembrane receptors rely on the membrane-proximal phosphotyrosine based sequence motifs (TBSMs) such as ITAM (immunoreceptor tyrosine-based activation motif), ITIM (immunoreceptor tyrosine-based inhibition motif) and signal transducer and activator of transcription 3 (STAT3)-recruiting YxxQ motifs. Tyrosine signal transducer and activator of transcription 3 Homo sapiens