Pub. Date : 2020 Aug 28
PMID : 32439420
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | LncRNA H19 downregulation confers erlotinib resistance through upregulation of PKM2 and phosphorylation of AKT in EGFR-mutant lung cancers. | Erlotinib Hydrochloride | H19 imprinted maternally expressed transcript | Homo sapiens |
| 2 | H19 downregulation contributed to erlotinib resistance through interaction and upregulation of PKM2, which enhanced the phosphorylation of AKT. | Erlotinib Hydrochloride | H19 imprinted maternally expressed transcript | Homo sapiens |
| 3 | These findings revealed a novel mechanism of low-level H19 in the regulation of erlotinib resistance in EGFR-mutant lung cancers. | Erlotinib Hydrochloride | H19 imprinted maternally expressed transcript | Homo sapiens |