Pub. Date : 2020
PMID : 32432042
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Here, we demonstrate that the alteration of iron homeostasis and the consequent increase of redox metabolism, mediated by the stable knock down of ferritin heavy chain (FtH), enhances the expression of CXCR4 in K562 erythroleukemia cells, thus promoting CXCL12-mediated motility. | Iron | ferritin heavy chain 1 | Homo sapiens |
2 | Here, we demonstrate that the alteration of iron homeostasis and the consequent increase of redox metabolism, mediated by the stable knock down of ferritin heavy chain (FtH), enhances the expression of CXCR4 in K562 erythroleukemia cells, thus promoting CXCL12-mediated motility. | Iron | ferritin heavy chain 1 | Homo sapiens |
3 | The effects of FtH dysregulation on CXCR4/CXCL12-mediated K562 cell motility extend the meaning of iron homeostasis in the leukemia cell microenvironment. | Iron | ferritin heavy chain 1 | Homo sapiens |