Pub. Date : 2020 Jun
PMID : 32418059
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Here, we report that doxorubicin synergizes with Smac mimetic to trigger TNF-mediated apoptosis, which is mechanistically distinct from doxorubicin-induced cell death. | Doxorubicin | tumor necrosis factor | Homo sapiens |
2 | These in vitro findings demonstrate that combination of Smac mimetic and doxorubicin synergistically triggers apoptosis through the TNF/CYLD/RIPK1/FADD/caspase-8 signaling pathway. | Doxorubicin | tumor necrosis factor | Homo sapiens |