Pub. Date : 2020 Jun 12
PMID : 32416094
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We report the crystal structure of RNF12 in complex with two of these E2 enzymes, as well as with an E2 ~ Ub conjugate in a closed conformation. | BM | ring finger protein, LIM domain interacting | Homo sapiens |
| 2 | Comparison of the RNF12 structure with other monomeric RINGs suggests that a loop prior to the core RING domain has a conserved and essential role in stabilisation of the active conformation of the bound E2 ~ Ub conjugate. | BM | ring finger protein, LIM domain interacting | Homo sapiens |