Title : Endosulfan triggers epithelial-mesenchymal transition via PTP4A3-mediated TGF-β signaling pathway in prostate cancer cells.

Pub. Date : 2020 Aug 20

PMID : 32413665






3 Functional Relationships(s)
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1 Endosulfan triggers epithelial-mesenchymal transition via PTP4A3-mediated TGF-beta signaling pathway in prostate cancer cells. Endosulfan protein tyrosine phosphatase 4A3 Homo sapiens
2 Endosulfan promoted cell migration and invasion, which were rescued by specific inhibitors for PTP4A3, TGF-beta signaling and Notch signaling, respectively. Endosulfan protein tyrosine phosphatase 4A3 Homo sapiens
3 These findings suggest that endosulfan promoted cell migration and invasion with the induction of EMT through PTP4A3-mediated TGF-beta signaling pathway in prostate cancer cells. Endosulfan protein tyrosine phosphatase 4A3 Homo sapiens