Pub. Date : 2020 Aug 20
PMID : 32413665
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Endosulfan triggers epithelial-mesenchymal transition via PTP4A3-mediated TGF-beta signaling pathway in prostate cancer cells. | Endosulfan | protein tyrosine phosphatase 4A3 | Homo sapiens |
2 | Endosulfan promoted cell migration and invasion, which were rescued by specific inhibitors for PTP4A3, TGF-beta signaling and Notch signaling, respectively. | Endosulfan | protein tyrosine phosphatase 4A3 | Homo sapiens |
3 | These findings suggest that endosulfan promoted cell migration and invasion with the induction of EMT through PTP4A3-mediated TGF-beta signaling pathway in prostate cancer cells. | Endosulfan | protein tyrosine phosphatase 4A3 | Homo sapiens |