Title : Progesterone receptor ligands for the treatment of endometriosis: the mechanisms behind therapeutic success and failure.

Pub. Date : 2020 Jun 18

PMID : 32412587






1 Functional Relationships(s)
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1 Among the molecular targets of progesterone in the normal endometrium that resist progestin action in endometriotic cells are the nuclear transcription factor FOXO1, matrix metalloproteinases, the transmembrane gap junction protein connexin 43 and paracrine regulators of estradiol metabolism. Progesterone forkhead box O1 Homo sapiens