Title : Effect of antidepressant drugs on the brain sphingolipid system.

Pub. Date : 2020 Jul

PMID : 32403969






5 Functional Relationships(s)
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1 Antidepressant-induced effects on mRNA expression for two key genes of the sphingolipid pathway, SMPD1 and ASAH1, were also measured by using quantitative real-time PCR. Sphingolipids sphingomyelin phosphodiesterase 1, acid lysosomal Mus musculus
2 The drug-induced decrease of sphingolipids coincided with reduced mRNA expression of two enzymes of the central sphingolipid pathway, i.e. acid sphingomyelinase (SMPD1) and acid ceramidase (ASAH1). Sphingolipids sphingomyelin phosphodiesterase 1, acid lysosomal Mus musculus
3 The drug-induced decrease of sphingolipids coincided with reduced mRNA expression of two enzymes of the central sphingolipid pathway, i.e. acid sphingomyelinase (SMPD1) and acid ceramidase (ASAH1). Sphingolipids sphingomyelin phosphodiesterase 1, acid lysosomal Mus musculus
4 The drug-induced decrease of sphingolipids coincided with reduced mRNA expression of two enzymes of the central sphingolipid pathway, i.e. acid sphingomyelinase (SMPD1) and acid ceramidase (ASAH1). Sphingolipids sphingomyelin phosphodiesterase 1, acid lysosomal Mus musculus
5 The drug-induced decrease of sphingolipids coincided with reduced mRNA expression of two enzymes of the central sphingolipid pathway, i.e. acid sphingomyelinase (SMPD1) and acid ceramidase (ASAH1). Sphingolipids sphingomyelin phosphodiesterase 1, acid lysosomal Mus musculus