Title : p53 dependent LGR5 inhibition and caspase 3 activation are critically involved in apoptotic effect of compound K and its combination therapy potential in HCT116 cells.

Pub. Date : 2020 Oct

PMID : 32403193






2 Functional Relationships(s)
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1 Conversely, caspase 3 inhibitor Z-DEVD-FMK reversed inhibitory effect of compound K on LGR5, c-Myc and procaspase3 in HCT116 cells. benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone caspase 3 Homo sapiens
2 Conversely, caspase 3 inhibitor Z-DEVD-FMK reversed inhibitory effect of compound K on LGR5, c-Myc and procaspase3 in HCT116 cells. benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone caspase 3 Homo sapiens