Pub. Date : 2020 Jul 1
PMID : 32401607
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The principal source of superoxide from the insulin-resistant endothelium is the Nox2 isoform of NADPH oxidase. | Superoxides | cytochrome b-245, beta polypeptide | Mus musculus |
| 2 | After 12 wk Western diet, ESMIRO/ApoE-/-/Nox2-/y mice had reduced EC superoxide generation and greater aortic relaxation to acetylcholine. | Superoxides | cytochrome b-245, beta polypeptide | Mus musculus |
| 3 | These results demonstrate that insulin resistance is characterized by increased Nox2-derived vascular superoxide. | Superoxides | cytochrome b-245, beta polypeptide | Mus musculus |