Pub. Date : 2020
PMID : 32390763
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | TUG1/miR-133b/CXCR4 axis regulates cisplatin resistance in human tongue squamous cell carcinoma. | Cisplatin | C-X-C motif chemokine receptor 4 | Homo sapiens |
| 2 | CXCR4 silence repressed cisplatin resistance, which was reversed by miR-133b knockdown. | Cisplatin | C-X-C motif chemokine receptor 4 | Homo sapiens |
| 3 | Conclusion: Downregulation of TUG1 impeded cisplatin resistance in TSCC-resistant cells by mediating miR-133b and CXCR4, indicating TUG1 as a promising target for TSCC chemotherapy. | Cisplatin | C-X-C motif chemokine receptor 4 | Homo sapiens |