Title : Design, synthesis and evaluation of novel nonquaternary and 3 non-oxime reactivators for acetylcholinesterase inhibited by organophosphates.

Pub. Date : 2020 Jul

PMID : 32388435






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1 Design, synthesis and evaluation of novel nonquaternary and 3 non-oxime reactivators for acetylcholinesterase inhibited by organophosphates. Oximes acetylcholinesterase (Cartwright blood group) Homo sapiens
2 A new series of novel nonquaternary conjugates and non-oxime reactivators for reactivation of both nerve agents and pesticides inhibited hAChE were described in this paper. Oximes acetylcholinesterase (Cartwright blood group) Homo sapiens
3 It was also found that some non-oxime derivatives of Mannich phenols displayed obvious reactivation potency for VX, sarin and pesticides inhibited hAChE even in very low concentration. Oximes acetylcholinesterase (Cartwright blood group) Homo sapiens