Title : Bisphenolic compounds alter gene expression in MCF-7 cells through interaction with estrogen receptor α.

Pub. Date : 2020 Jul 15

PMID : 32387340






3 Functional Relationships(s)
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1 We applied next generation sequencing (NGS) with the estrogen receptor alpha (ERalpha) positive human breast cancer cell line MCF-7 treated with 17-beta-estradiol (E2), bisphenol A (BPA), bisphenol B (BPB), bisphenol Z (BPZ) and tetramethyl bisphenol A (4MeBPA). bisphenol A estrogen receptor 1 Homo sapiens
2 We applied next generation sequencing (NGS) with the estrogen receptor alpha (ERalpha) positive human breast cancer cell line MCF-7 treated with 17-beta-estradiol (E2), bisphenol A (BPA), bisphenol B (BPB), bisphenol Z (BPZ) and tetramethyl bisphenol A (4MeBPA). bisphenol A estrogen receptor 1 Homo sapiens
3 We further confirmed the binding, activation and proliferative effect of BPA, BPB, BPZ, and 4MeBPA on ERalpha. bisphenol A estrogen receptor 1 Homo sapiens