Title : Enhanced insulin receptor interaction by a bifunctional insulin-transferrin fusion protein: an approach to overcome insulin resistance.

Pub. Date : 2020 May 7

PMID : 32382087






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We found that, with the assistance of the transferrin moiety binding to the transferrin receptor, the activated ProINS-Tf exhibited significantly higher binding affinity to the insulin receptor compared with the native insulin, resulting in a prolonged and stronger Akt phosphorylation. proins-tf transferrin receptor Mus musculus