Pub. Date : 2020
PMID : 32370715
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Upregulation of miR-496 rescues propofol-induced neurotoxicity by targeting Rho Associated Coiled-Coil Containing Protein Kinase 2 (ROCK2) in prefrontal cortical neurons. | Propofol | Rho associated coiled-coil containing protein kinase 2 | Homo sapiens |
| 2 | Upregulation of miR-496 rescues propofol-induced neurotoxicity by targeting Rho Associated Coiled-Coil Containing Protein Kinase 2 (ROCK2) in prefrontal cortical neurons. | Propofol | Rho associated coiled-coil containing protein kinase 2 | Homo sapiens |
| 3 | Besides, propofol increased the expression of ROCK2 through inhibiting miR-496 in PFC neurons. | Propofol | Rho associated coiled-coil containing protein kinase 2 | Homo sapiens |
| 4 | CONCLUSION: miR-496 was decreased in PFC neurons treated with propofol, and overexpression of miR-496 attenuated propofol-induced neurotoxicity by targeting ROCK2. | Propofol | Rho associated coiled-coil containing protein kinase 2 | Homo sapiens |
| 5 | CONCLUSION: miR-496 was decreased in PFC neurons treated with propofol, and overexpression of miR-496 attenuated propofol-induced neurotoxicity by targeting ROCK2. | Propofol | Rho associated coiled-coil containing protein kinase 2 | Homo sapiens |
| 6 | miR-496 and ROCK2 may be promising targets for protecting propofol-induced neurotoxicity. | Propofol | Rho associated coiled-coil containing protein kinase 2 | Homo sapiens |