Pub. Date : 2020
PMID : 32368398
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cisplatin sensitivity mediated by NKX2-1 in lung adenocarcinoma is dependent on p53 mutational status via modulating TNFSF10 expression. | Cisplatin | TNF superfamily member 10 | Homo sapiens |
| 2 | TNFSF10 was identified in a microarray analysis as a potential candidate responsible for NKX2-1-mediated apoptosis induced by cisplatin. | Cisplatin | TNF superfamily member 10 | Homo sapiens |
| 3 | In summary, modulation of TNFSF10 expression by NKX2-1 may be a potential indicator for predicting the response to cisplatin-based chemotherapy in patients with lung adenocarcinomas. | Cisplatin | TNF superfamily member 10 | Homo sapiens |