Title : Pharmacological inhibition and knockdown of O-GlcNAcase reduces cellular internalization of α-synuclein preformed fibrils.

Pub. Date : 2021 Jan

PMID : 32365408






1 Functional Relationships(s)
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1 Here we show that Thiamet-G, a highly selective pharmacological agent that inhibits the glycoside hydrolase O-GlcNAcase (OGA), blunts the cellular uptake of alpha-synuclein fibrils. thiamet O-GlcNAcase Mus musculus