Title : Co-inhibition of BCL-XL and MCL-1 with selective BCL-2 family inhibitors enhances cytotoxicity of cervical cancer cell lines.

Pub. Date : 2020 Jul

PMID : 32346617






2 Functional Relationships(s)
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1 In this present study, we used the BCL-2 selective inhibitor ABT-199 and the BCL-XL selective inhibitor A1331852 to resolve the individual antitumor activities of ABT-263 into BCL-2 and BCL-XL dependent mechanisms. A-1331852 BCL2 like 1 Homo sapiens
2 Co-inhibition of BCL-XL and MCL-1 with A1331852 and S63845 significantly inhibited cell proliferation of all four cell lines. A-1331852 BCL2 like 1 Homo sapiens