Pub. Date : 2020
PMID : 32328192
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | LncRNA UCA1 promotes cisplatin resistance in gastric cancer via recruiting EZH2 and activating PI3K/AKT pathway. | Cisplatin | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Hence, UCA1 promotes cisplatin resistance of GC via recruiting EZH2 and activating PI3K/AKT pathway. | Cisplatin | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | Conclusion: Our research revealed the lncRNA UCA1 promoted the cisplatin resistance of GC by recruiting EZH2 and activating PI3K/AKT pathway to modulate cell apoptosis, indicating treatments targeting UCA1 or EZH2 might provide meaningful therapeutic strategies for cisplatin-resistance GC patients. | Cisplatin | AKT serine/threonine kinase 1 | Homo sapiens |