Title : Targeting Rac and Cdc42 GEFs in Metastatic Cancer.

Pub. Date : 2020

PMID : 32322580






1 Functional Relationships(s)
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1 Rac and Cdc42 are often dysregulated in cancer due to hyperactivation by guanine nucleotide exchange factors (GEFs), belonging to both the diffuse B-cell lymphoma (Dbl) and dedicator of cytokinesis (DOCK) families. Guanine Nucleotides MCF.2 cell line derived transforming sequence Homo sapiens