Title : Pharmacological Characterization of the Microsomal Prostaglandin E2 Synthase-1 Inhibitor AF3485 In Vitro and In Vivo.

Pub. Date : 2020

PMID : 32317963






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Rationale: The development of inhibitors of microsomal prostaglandin (PG)E2 synthase-1 (mPGES-1) was driven by the promise of attaining antiinflammatory agents with a safe cardiovascular profile because of the possible diversion of the accumulated substrate, PGH2, towards prostacyclin (PGI2). Prostaglandin H2 prostaglandin E synthase Mus musculus