Title : Androgens stimulate erythropoiesis through the DNA-binding activity of the androgen receptor in non-hematopoietic cells.

Pub. Date : 2020 Sep

PMID : 32311143






3 Functional Relationships(s)
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1 DESIGN AND METHODS: To identify the androgen signalling pathway, we treated male mice lacking the second zinc finger of the DNA binding domain of the AR (AR ZF2 ) with non-aromatizable 5alpha-dihydrotestosterone (5alpha-DHT), or aromatizable testosterone. Dihydrotestosterone androgen receptor Mus musculus
2 DESIGN AND METHODS: To identify the androgen signalling pathway, we treated male mice lacking the second zinc finger of the DNA binding domain of the AR (AR ZF2 ) with non-aromatizable 5alpha-dihydrotestosterone (5alpha-DHT), or aromatizable testosterone. Dihydrotestosterone androgen receptor Mus musculus
3 Female wild-type mice reconstituted with AR ZF2 bone marrow cells remained responsive to 5alpha-DHT. Dihydrotestosterone androgen receptor Mus musculus