Pub. Date : 2020 May
PMID : 32301004
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The role of PSMB5 in sodium arsenite-induced oxidative stress in L-02 cells. | sodium arsenite | proteasome 20S subunit beta 5 | Homo sapiens |
| 2 | This paper aims to study the role and mechanism of PSMB5 in sodium arsenite (NaAsO2)-induced oxidative stress liver injury in L-02 cells. | sodium arsenite | proteasome 20S subunit beta 5 | Homo sapiens |
| 3 | This paper aims to study the role and mechanism of PSMB5 in sodium arsenite (NaAsO2)-induced oxidative stress liver injury in L-02 cells. | sodium arsenite | proteasome 20S subunit beta 5 | Homo sapiens |
| 4 | The results demonstrated that NaAsO2 could induce oxidative stress-induced liver injury and the activity of 20S proteasome and the protein expression of PSMB5, SOD1, and GPx1 decreased. | sodium arsenite | proteasome 20S subunit beta 5 | Homo sapiens |
| 5 | After MG132 or PSMB5-siRNA pretreatment, and then L-02 cells were treated with NaAsO2, the gene expression of PSMB remarkably decreased; however, the protein expression of SOD1 and GPx1 increased. | sodium arsenite | proteasome 20S subunit beta 5 | Homo sapiens |
| 6 | Overall, NaAsO2 exposure could induce oxidative stress liver injury and low expression of PSMB5 in L-02 cells, and PSMB5 might play an important role in the regulation of oxidative stress by regulating the expression of SOD1 and Gpx1. | sodium arsenite | proteasome 20S subunit beta 5 | Homo sapiens |