Title : Association Between Homocysteine Level and Methylenetetrahydrofolate Reductase Gene Polymorphisms in Type 2 Diabetes Accompanied by Dyslipidemia.

Pub. Date : 2020 Mar 31

PMID : 32299541






4 Functional Relationships(s)
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1 Objective To investigate the association between total homocysteine (tHcy) level in plasma and methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C genetic polymorphisms in a Chinese Han nationality population with type 2 diabetes mellitus (T2DM) accompanied by dyslipidemia. thcy methylenetetrahydrofolate reductase Homo sapiens
2 Objective To investigate the association between total homocysteine (tHcy) level in plasma and methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C genetic polymorphisms in a Chinese Han nationality population with type 2 diabetes mellitus (T2DM) accompanied by dyslipidemia. thcy methylenetetrahydrofolate reductase Homo sapiens
3 There was a significant correlation between tHcy level and MTHFR C677T gene polymorphism in T2DM patients (t=2.27, P=0.02). thcy methylenetetrahydrofolate reductase Homo sapiens
4 Conclusion MTHFR 677TT genotype might associate with higher tHcy level in T2DM patients with dyslipidemia. thcy methylenetetrahydrofolate reductase Homo sapiens