Title : Sirtuin 1 deficiency decreases bone mass and increases bone marrow adiposity in a mouse model of chronic energy deficiency.

Pub. Date : 2020 Jul

PMID : 32289519






2 Functional Relationships(s)
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Protein Name
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1 After a 10-day organotypic culture, tibias from SBA mice displayed low levels of Sirt1 mRNA which are restored by resveratrol treatment. Resveratrol sirtuin 1 Mus musculus
2 In contrast of down-regulation of Sirt1 expression induced by sirtinol treatment, stimulation of Sirt1 expression by resveratrol lead to a decrease in adipogenesis and increase in osteogenesis. Resveratrol sirtuin 1 Mus musculus