Title : The Accumulation of Psoralen Contributes to Its Hepatotoxicity Revealed by Pharmacokinetic and Toxicokinetic Study after Repeated Administration.

Pub. Date : 2020 Apr 7

PMID : 32280872






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 HepG2 cells were exposed to low doses (5, 10, 20, or 40 muM) of psoralen for 1, 2, 3, or 4 days. Ficusin latexin Homo sapiens
2 A 20 and 40 muM dose of psoralen did not induced cell death in the 1st day but significantly decreased the cell viability at the 3rd and 4th day of repeated administration, respectively. Ficusin latexin Homo sapiens