Title : Vav1 and mutant K-Ras synergize in the early development of pancreatic ductal adenocarcinoma in mice.

Pub. Date : 2020 May

PMID : 32277014






2 Functional Relationships(s)
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1 Treatment of K-RasG12D and K-RasG12D/Vav1 mice with azathioprine, an immune-suppressor drug which inhibits Vav1"s activity as a GDP/GTP exchange factor, dramatically reduced the number of malignant lesions. Azathioprine vav 1 oncogene Mus musculus
2 Treatment of K-RasG12D and K-RasG12D/Vav1 mice with azathioprine, an immune-suppressor drug which inhibits Vav1"s activity as a GDP/GTP exchange factor, dramatically reduced the number of malignant lesions. Azathioprine vav 1 oncogene Mus musculus