Pub. Date : 2020 Jun
PMID : 32272432
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Tubeimoside I improves survival of mice in sepsis by inhibiting inducible nitric oxide synthase expression. | tubeimoside I | nitric oxide synthase 2, inducible | Mus musculus |
| 2 | CLP activated TLR4-MyD88-NF-kappaB-iNOS pathway was also inhibited by TBM both. | tubeimoside I | nitric oxide synthase 2, inducible | Mus musculus |
| 3 | However, iNOS gene knockout counteracted the protection provided by TBM. | tubeimoside I | nitric oxide synthase 2, inducible | Mus musculus |
| 4 | We conclude that TBM protects mice in sepsis by reducing excessive NO production through inhibiting the TLR4-MyD88-NF-kappaB-iNOS pathway. | tubeimoside I | nitric oxide synthase 2, inducible | Mus musculus |