Title : Aquaporin-3 in the epidermis: more than skin deep.

Pub. Date : 2020 Jun 1

PMID : 32267715






3 Functional Relationships(s)
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1 Accumulating evidence in the literature indicates that the water-, glycerol-, and hydrogen peroxide-transporting channel aquaporin-3 (AQP3) plays a key role in various processes involved in keratinocyte function, and abnormalities in this channel have been observed in several human skin diseases. Water aquaporin 3 (Gill blood group) Homo sapiens
2 Accumulating evidence in the literature indicates that the water-, glycerol-, and hydrogen peroxide-transporting channel aquaporin-3 (AQP3) plays a key role in various processes involved in keratinocyte function, and abnormalities in this channel have been observed in several human skin diseases. Water aquaporin 3 (Gill blood group) Homo sapiens
3 Here, we discuss the data linking AQP3 to keratinocyte proliferation, migration, differentiation, and survival as well as its role in skin properties and functions like hydration, water retention, wound healing, and barrier repair. Water aquaporin 3 (Gill blood group) Homo sapiens