Title : Phosphorylation of vaccinia-related kinase 1 at threonine 386 transduces glucose stress signal in human liver cells.

Pub. Date : 2020 Apr 30

PMID : 32266931






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Both c-Jun and p53 are phosphorylated at Ser63 and Thr18, respectively, in response to low glucose (40 mg/dL of medium) but not high glucose (140 mg/dL of medium) in human hepatoma-derived Huh-7 cells. Glucose tumor protein p53 Homo sapiens
2 Both c-Jun and p53 are phosphorylated at Ser63 and Thr18, respectively, in response to low glucose (40 mg/dL of medium) but not high glucose (140 mg/dL of medium) in human hepatoma-derived Huh-7 cells. Glucose tumor protein p53 Homo sapiens
3 A correlation of this low glucose response phosphorylation of Thr386 with the phosphorylation of c-Jun and p53 suggests that VRK1 phosphorylated at Thr386 catalyzes this phosphorylation. Glucose tumor protein p53 Homo sapiens