Title : Hydroxychloroquine Mitigates the Production of 8-Isoprostane and Improves Vascular Dysfunction: Implications for Treating Preeclampsia.

Pub. Date : 2020 Apr 3

PMID : 32260307






2 Functional Relationships(s)
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1 However, hydroxychloroquine mitigated TNF-alpha-induced HUVEC production of 8-isoprostane and Nicotinanamide adenine dinucleotide phosphate (NADPH) oxidase expression. Hydroxychloroquine tumor necrosis factor Homo sapiens
2 Hydroxychloroquine also mitigated TNF-alpha and preeclamptic serum-induced HUVEC monolayer permeability and rescued the loss of zona occludens protein zona occludens 1 (ZO-1). Hydroxychloroquine tumor necrosis factor Homo sapiens