Title : A role for TNF-α in alveolar macrophage damage-associated molecular pattern release.

Pub. Date : 2020 May 7

PMID : 32255768






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 We found that phagocytosis of Be led to AM cell death independently of caspase, RIP1K, RIP3K or ROS activity. Beryllium caspase 8 Mus musculus
2 Prior to cell death, Be-exposed AMPhis secreted TNFalpha that boosted intracellular stores of IL-1alpha followed by caspase 8-dependent fragmentation of DNA. Beryllium caspase 8 Mus musculus