Pub. Date : 2018 Nov 21
PMID : 32254583
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Herein, a novel SMND of carboplatin-lauric acid nanoparticles (CBP-LA NPs) was developed for the first time to reduce GSH-mediated platinum resistance and improve the antitumor efficiency of platinum(ii). | Platinum | CREB binding protein | Homo sapiens |
2 | Herein, a novel SMND of carboplatin-lauric acid nanoparticles (CBP-LA NPs) was developed for the first time to reduce GSH-mediated platinum resistance and improve the antitumor efficiency of platinum(ii). | Platinum | CREB binding protein | Homo sapiens |
3 | The intracellular glutathione determination and the Pt-DNA adduct assay revealed that CBP-LA NPs could reduce the intracellular GSH levels and improve the efficiency of platinum chelating with DNA, which would overcome GSH-mediated platinum(ii) resistance. | Platinum | CREB binding protein | Homo sapiens |
4 | The intracellular glutathione determination and the Pt-DNA adduct assay revealed that CBP-LA NPs could reduce the intracellular GSH levels and improve the efficiency of platinum chelating with DNA, which would overcome GSH-mediated platinum(ii) resistance. | Platinum | CREB binding protein | Homo sapiens |