Title : Synthetic glycopolymers as modulators of protein aggregation: influences of chemical composition, topology and concentration.

Pub. Date : 2018 Feb 21

PMID : 32254292






1 Functional Relationships(s)
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1 Accelerated stability studies of the highly concentrated mAb solutions (50 mg mL-1) revealed that the increased glycopolymer concentrations generally decreased the mAb stability, as judged by the amount of mAb1 "monomer" molecules in solution, with star- and linear-trehalose glycopolymers further generating visible aggregates. glycopolymer L1 cell adhesion molecule Mus musculus