Pub. Date : 2020 Apr
PMID : 32246833
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | CONCLUSIONS: Our findings indicate that TNFalpha treatment reduces steroid hormone production in MG63 cells (but not in HOB) at the level of lanosterol-demethylation during cholesterol biosynthesis. | Steroids | tumor necrosis factor | Homo sapiens |
| 2 | By contrast, TNFalpha treatment of HOB cells (but not in MG63) leads to the upregulation of several key enzymes involved in the biosynthesis of sex steroids, which is proposed to lead to higher levels of estrogen production. | Steroids | tumor necrosis factor | Homo sapiens |