Title : Host Defense Peptide RNase 7 Is Down-regulated in the Skin of Diabetic Patients with or without Chronic Ulcers, and its Expression is Altered with Metformin.

Pub. Date : 2020 May

PMID : 32229156






2 Functional Relationships(s)
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1 To assess whether L-isoleucine, calcitriol, phenyl butyrate, metformin, glyburide or insulin induced RNase 7, keratinocytes were stimulated, and RNase 7 expression was evaluated. Glyburide ribonuclease A family member 7 Homo sapiens
2 Since most of the DM2 patients are treated with drugs to reduce glycemia, we investigated whether glyburide, metformin or insulin were able to induce any change regarding RNase 7 production. Glyburide ribonuclease A family member 7 Homo sapiens