Pub. Date : 2020 Jul 1
PMID : 32222543
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The increase in enzymatic activity with celastrol correlated with an increase in the transcriptional and proteome levels of the heat shock proteins Hsp90 and Hsp70. | celastrol | heat shock protein family A (Hsp70) member 4 | Homo sapiens |
| 2 | The use of specific Hsp70 or Hsp90 inhibitors showed the positive effect of celastrol on PMM2 stability and activity to occur through Hsp90-driven modulation of the proteostasis network. | celastrol | heat shock protein family A (Hsp70) member 4 | Homo sapiens |