Title : Icariin affects cell cycle progression and proliferation of human retinal pigment epithelial cells via enhancing expression of H19.

Pub. Date : 2020

PMID : 32219038






4 Functional Relationships(s)
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1 Most importantly, H19 was positively regulated by ICA and H19 depletion could reverse the inhibitory effects of ICA on cell cycle progression and proliferation in PDGF-BB-stimulated RPE cells. icariin H19 imprinted maternally expressed transcript Homo sapiens
2 Most importantly, H19 was positively regulated by ICA and H19 depletion could reverse the inhibitory effects of ICA on cell cycle progression and proliferation in PDGF-BB-stimulated RPE cells. icariin H19 imprinted maternally expressed transcript Homo sapiens
3 Most importantly, H19 was positively regulated by ICA and H19 depletion could reverse the inhibitory effects of ICA on cell cycle progression and proliferation in PDGF-BB-stimulated RPE cells. icariin H19 imprinted maternally expressed transcript Homo sapiens
4 Further mechanical explorations showed that H19 knockdown resulted in alternative expressions levels of cyclin D1, CDK4, CDK6, p21 and p53 under ICA treatment. icariin H19 imprinted maternally expressed transcript Homo sapiens