Title : A photo-triggerable aptamer nanoswitch for spatiotemporal controllable siRNA delivery.

Pub. Date : 2020 May 28

PMID : 32207496






1 Functional Relationships(s)
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1 Recognition between AS1411 and nucleolin was effectively blocked by a photo-labile complementary oligonucleotide, which could be reactivated with photo-irradiation, resulting in efficient tumor-targeted siRNA internalization and gene silencing in vitro and in vivo. Oligonucleotides nucleolin Homo sapiens